Tuberculosis

Tuberculosis is a significant infectious disease caused by the bacterium *Mycobacterium tuberculosis*. While commonly known for its primary effect on the lungs, the infection has the potential to disseminate and affect various parts of the body, including the bones, kidneys, and central nervous system. The bacteria can establish a chronic, latent state within the host, which may become active years later, particularly if the host's immune defenses are compromised. Diagnosis relies on identifying the pathogen in bodily fluids and the management of the disease requires prolonged, combination antimicrobial therapy to ensure the complete elimination of the bacteria and prevent the development of drug resistance.