Stress (biology)

Stress is a biological systemic response triggered by perceived challenges or threats from the internal or external environment. Physiologically, the initial stages of stress activate the sympathetic nervous system and the endocrine axis, leading to the rapid release of stress hormones such as cortisol and adrenaline. This mobilization of resources facilitates immediate survival responses, often characterized by heightened alertness and increased metabolic activity. When stress becomes chronic, however, the sustained elevation of these hormonal agents can lead to allostatic load, resulting in the dysregulation of multiple body systems. This prolonged state of alarm can compromise immune function, negatively impact cardiovascular health, and disrupt metabolic and cognitive processes, demonstrating a maladaptive response when the threat is persistent rather than transient.