The skin is the largest organ of the body and serves as the primary physical barrier between the internal environment and the external world. Its structure is layered, comprising the epidermis, which is the outermost protective layer; the dermis, a layer rich in connective tissues and vasculature; and the hypodermis, which anchors the skin to underlying structures. Functionally, the skin provides extensive defense against pathogens and physical trauma while also playing crucial roles in thermoregulation through sweat gland activity and blood vessel dilation. It is also a sensory organ, containing various nerve receptors that allow for the detection of touch, pressure, pain, and temperature.