Psychosis is a syndrome characterized by a profound break from reality, involving significant disturbances in thought process, perception, and behavior. Core manifestations include delusions, which are firmly held, false beliefs not grounded in reality, and hallucinations, which are sensory perceptions experienced without external stimuli. The underlying etiology is understood to involve dysregulation within various brain circuits, affecting neurotransmitter systems and cognitive function. Diagnosis relies on assessing the severity of these symptoms, which can lead to functional impairments in daily life. Treatment is multimodal, involving pharmacological agents to stabilize neurotransmitter activity and therapeutic interventions aimed at managing symptoms and improving overall cognitive and functional capacity.