Mushroom poisoning results from the ingestion of psychoactive or nephrotoxic fungi that contain various secondary metabolites. These toxins can affect multiple organ systems, leading to symptoms ranging from gastrointestinal distress and nausea to severe liver or kidney damage, depending on the specific compound and the concentration of the dose. Diagnosis involves identifying the toxic agent and monitoring vital signs and organ function markers. Treatment is largely supportive, focusing on maintaining hydration, managing symptoms, and providing gastrointestinal decontamination to mitigate further absorption of the harmful compounds. Prevention relies on education regarding the proper identification of edible fungi and recognizing the dangers of consuming unverified wild specimens.