Injury

Injury refers to any trauma or damage inflicted upon biological tissues, which initiates a complex cascade of physiological responses designed to mitigate ongoing damage and facilitate tissue repair. The initial event disrupts structural integrity, potentially involving mechanical forces, chemical agents, or thermal extremes, leading to local cellular distress and hemorrhage. This triggers the inflammatory response, a critical biological process involving the recruitment of immune cells and the release of signaling molecules. Following the inflammatory phase, the process transitions into proliferation and remodeling, where damaged components are cleared and structural materials, such as collagen and new connective tissue, are synthesized to restore the injured area toward its previous functional state.