Acne vulgaris is a common inflammatory skin condition characterized by the formation of comedones, or clogged pores. Its development involves a combination of factors, primarily the excessive production of sebum by the sebaceous glands, the accumulation of dead skin cells that physically block the pore opening, and the proliferation of commensal bacteria within the follicle. This initial blockage leads to comedones, which can progress if the follicular contents become trapped and inflamed. Treatment strategies involve modifying skin cell turnover rates, reducing sebum production, and applying antimicrobial agents to manage the associated bacterial overgrowth and inflammation. Management is typically approached through topical medications or systemic treatments aimed at normalizing skin function and reducing pathological inflammation.